The success of CTLA4, PD-1, and PD-L1 inhibitors paved the way for researchers to explore the vast therapeutic potential of immune checkpoint modulation, enabling the discovery of product candidates against clinical conditions beyond oncology
Roots Analysis has announced the addition of “Next Generation Immune Checkpoint Inhibitors and Stimulators Market, 2020-2030” report to its list of offerings.
Over time, significant strides have been made in immune checkpoint research, resulting in the discovery of several inhibitory (LAG-3, TIM-3, TIGIT, VISTA and B7-H3) and stimulatory receptors (OX40, ICOS, GITR, 4-1BB and CD40), which are being investigated as potential targets for therapy development. Further, studies of combinatorial immune checkpoint blockade / co-stimulation, targeting newly identified checkpoints along with known checkpoint inhibitor therapies, have demonstrated promising clinical outcomes as well.
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